5/11/2007

 

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Cities that instituted quarantine, school closings, bans on public gatherings and other such procedures early in the epidemic had peak death rates 30 percent to 50 percent lower than those that did not. "It had been received wisdom that these interventions didn't work" Richard Hatchett, the lead author of one of the studies, "because they looked at the variability between cities and concluded that there was some other factor than the interventions that caused the differing outcomes. Adolescents responded better than children to treatment for depression and anxiety, the researchers found. But 50 percent of depressed patients taking dummy pills also improved.
Two weeks before Philadelphia officials began to react, doctors in St. And two days after the first civilian cases, police officers helped the department enforce a shutdown of schools, churches and other gathering places. Louis were 347 per 100,000 people, less than half the rate in Philadelphia. Hatchett said, "is a function of a lot of modeling work that we did previously."
As these numbers increase, the epidemic fades. Ferguson said, is to tune an imperfect intervention perfectly so that a single peak of minimal size is the result. Ferguson said, "we would start a crash program to make a vaccine. Demographic studies show that the population most at risk is single, urban, substance-abusing older white men with physical illness, few supports and low incomes. In our last meeting, before he stopped coming to appointments, he told me that he had joined the site to meet friends.
Finding him there after death seemed imperative. Some voiced hopes of meeting one day, some had comments about other correspondents on the site, some sent good wishes on relevant holidays.
I had gone on the site only a day after his death, but his cyberobituary must have traveled faster. By now, of course, the messages had no recipient, and the friends my patient had made were writing to one another. One of the most notable occurred at the Johns Hopkins University School of Medicine, where educators initiated a formal system to train students on the clinical wards. At the same time, professors at Johns Hopkins and elsewhere instituted early versions of modern residency training programs, in which residents — newly minted doctors — learned their profession on the wards from attending physicians and, in turn, taught students. Wolfberg wrote in the same journal last month, for years medical students performed pelvic examinations on anesthetized women who had not given consent because senior obstetricians said it was the best way to learn internal anatomy. But when he told the resident, who had seen the patient earlier and more quickly, the resident refused to re-examine the patient. He then reminded the student that while he had examined hundreds of such cases, the student had seen only a few.
The student admitted that he was far from positive that something was seriously wrong. What should a medical student do in such a situation? One possibility is to take the matter up with a more senior doctor. Adolescents responded better than children to treatment for depression and anxiety, the researchers found.
They also found that only Prozac worked better than dummy pills in depressed children younger than 12. But he said the suicidal behavior risk, although lower than found by the F.D.A., demanded that doctors and families watch for warning signs.Louis persuaded the city to require that influenza cases be registered with the health department. And two days after the first civilian cases, police officers helped the department enforce a shutdown of schools, churches and other gathering places. "You can't treat kids with these drugs without taking this information into account," said Dr. And two days after the first civilian cases, police officers helped the department enforce a shutdown of schools, churches and other gathering places. Early action appeared to have saved thousands of lives.
This month, researchers published two new studies in The Proceedings of the National Academy of Sciences comparing public-health responses in cities like St. Using mathematical models, they reported that such large differences in death rates could be explained by the ways the cities carried out prevention measures, especially in their timing. A two-week difference in response times, according to the researchers, is long enough for the number of people infected in an influenza epidemic to double three to five times. As these numbers increase, the epidemic fades.
Louis, Milwaukee and Kansas City, Mo., had the most effective prevention programs, and time was of the essence. I knew about his voices, and sometimes knew what his voices told him, but had come to believe that voices and patient coexisted in a delicate yet stable ecosystem. The criteria are so specific it's like putting pins in a war map. Some voiced hopes of meeting one day, some had comments about other correspondents on the site, some sent good wishes on relevant holidays. In this world, he was a Pisces, not a schizophrenic.
The last dozen messages on the screen were exactly the same. At the same time, professors at Johns Hopkins and elsewhere instituted early versions of modern residency training programs, in which residents — newly minted doctors — learned their profession on the wards from attending physicians and, in turn, taught students.
Wolfberg wrote in the same journal last month, for years medical students performed pelvic examinations on anesthetized women who had not given consent because senior obstetricians said it was the best way to learn internal anatomy. Although this practice made many students uncomfortable, most were afraid to speak up. And in the studies of anxiety disorders, 69 percent improved on antidepressants and 39 percent improved on dummy pills. Infected people were quarantined in their homes. Using mathematical models, they reported that such large differences in death rates could be explained by the ways the cities carried out prevention measures, especially in their timing. Cities that instituted quarantine, school closings, bans on public gatherings and other such procedures early in the epidemic had peak death rates 30 percent to 50 percent lower than those that did not. "It had been received wisdom that these interventions didn't work"
Richard Hatchett, the lead author of one of the studies, "because they looked at the variability between cities and concluded that there was some other factor than the interventions that caused the differing outcomes. Who is a researcher at the National Institutes of Health, said the findings might hold lessons for the 21st century. In an influenza epidemic, a certain number of people survive the illness and are immune to reinfection.
As these numbers increase, the epidemic fades. But he said the suicidal behavior risk, although lower than found by the F.D.A., demanded that doctors and families watch for warning signs.Louis persuaded the city to require that influenza cases be registered with the health department. This month, researchers published two new studies in The Proceedings of the National Academy of Sciences comparing public-health responses in cities like St. Who is a researcher at the National Institutes of Health, said the findings might hold lessons for the 21st century. A two-week difference in response times, according to the researchers, is long enough for the number of people infected in an influenza epidemic to double three to five times. But an effective prevention program without a vaccine can leave enough people uninfected and still susceptible to the virus to start the epidemic again as soon as the controls are lifted.
14, 1918 — in high spirits three days after the armistice that ended the war, and with influenza cases declining — the city reopened schools and businesses. Two weeks later, the second wave of the epidemic struck, this time with children making up 30 percent to 40 percent of the infections. Among young patients with obsessive-compulsive disorders, 52 percent improved on antidepressants, compared with 32 percent who improved on dummy pills. "You can't say, 'Take these and call me in six weeks. "
And two days after the first civilian cases, police officers helped the department enforce a shutdown of schools, churches and other gathering places. Early action appeared to have saved thousands of lives. Scientists are still studying the 1918 pandemic, the deadliest of the 20th century, looking for lessons for future outbreaks — including the possibility that H5N1, the avian influenza virus, could mutate into a form spread easily from human to human. Among young patients with obsessive-compulsive disorders, 52 percent improved on antidepressants, compared with 32 percent who improved on dummy pills. "You can't say, 'Take these and call me in six weeks. "
Louis were 347 per 100,000 people, less than half the rate in Philadelphia. Scientists are still studying the 1918 pandemic, the deadliest of the 20th century, looking for lessons for future outbreaks — including the possibility that H5N1, the avian influenza virus, could mutate into a form spread easily from human to human.
Hatchett said, "is a function of a lot of modeling work that we did previously." As these numbers increase, the epidemic fades. 14, 1918 — in high spirits three days after the armistice that ended the war, and with influenza cases declining — the city reopened schools and businesses. Two weeks later, the second wave of the epidemic struck, this time with children making up 30 percent to 40 percent of the infections. They also found that only Prozac worked better than dummy pills in depressed children younger than 12. But 50 percent of depressed patients taking dummy pills also improved. But he said the suicidal behavior risk, although lower than found by the F.D.A., demanded that doctors and families watch for warning signs.
March, who was not involved in the study but who does similar research. This month, researchers published two new studies in The Proceedings of the National Academy of Sciences comparing public-health responses in cities like St. A two-week difference in response times, according to the researchers, is long enough for the number of people infected in an influenza epidemic to double three to five times.
The director for global migration and quarantine at the federal Centers for Disease Control and Prevention in Atlanta, found reason for optimism in the study results. The second study, in the same issue of The Proceedings, suggests that in one sense preventive measures can be too effective.




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